Idaho History Jan 2, 2022

Idaho 1918-1920 Influenza Pandemic

Part 87

Idaho Newspaper Clippings March 17-19, 1920

Idaho photos courtesy: the Mike Fritz Collection, History of Idaho
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March 17

The Challis Messenger., March 17, 1920, Page 1


Gone Home

On Wednesday of last week, this community lost one of its highly esteemed ladies.

After a protracted illness and intense suffering, Mrs. Mary Kieupfer departed this life at her home in this city at 7 a.m.

She was born in Helsinborg, Sweden, March 4, 1854, and came to the United States in 1888 with her three little daughters to join her husband in Custer Idaho, as he had some ahead to prepare a home for them.

A few months after locating in Custer, the entire family was caught in a snowslide. She and her husband had a narrow escape but the little girls lost their lives. Being a woman of true Christian faith, she bravely bore her loss.

She was ever ready to answer the call of distress or sickness, and was a devoted mother and a staunch friend.

Since coming to Custer county her genial manner has won her a host of friends.

We shall miss her but what a blessing to know that she is now reaping her reward and is united with her loved ones who awaited her on the other shore. …

Besides a host of friends, she leaves a daughter, two sons, a grand son, a sister and three brothers to mourn her loss.

The sympathy of the entire community goes out to the bereaved family.
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Card of Thanks

We take this opportunity to thank our many friends for their thoughtful kindness during the illness and the passing away of our beloved mother.

George and Elva Johnson
Lilly and Earl Millick
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Card of Thanks

I wish to extend my heartfelt thanks to all those friends who came to my assistance and rendered their kindness in so many ways, during the illness, death and burial of my beloved ones.

Mrs. Eileen Frazier Tracht

source: The Challis Messenger. (Challis, Idaho), 17 March 1920. Chronicling America: Historic American Newspapers. Lib. of Congress.
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The Challis Messenger., March 17, 1920, Page 4

Beware of Auto Flu

If your car has a fever, sneezes and coughs, and then lays down – call a specialist. Phone 28, (3 rings) Challis, Ida, specialists in troubleshooting.

Preventative of Auto Flu

See that your car has a full outfit of our new rubbers on its feet. Have it examined and adjusted here and you will be ready for a good, healthy, summer’s work.

Transcontinental Garage
Challis, Idaho
Edwin Woffinden – Albert Woffinden, Mgr.

(ibid, page 4)
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The Challis Messenger., March 17, 1920, Page 5

Items About People You Know

Nickerson Ill — Frank Nickerson was taken very ill last Friday night and for awhile his life was despaired of. He is much improved at this time and contemplates leaving soon for the outside for medical attention.

Much Improved — John Stephens, who was reported as seriously ill last week is much improved and is apparently on the road to recovery.

Unimproved — J. H. Van Camp, who has been suffering from a severe rheumatic attack for some time past, is unimproved.

St. Patrick’s Day — Today is St. Patrick’s Day and is being celebrated throughout the country in honor of the saint who drove the snakes out of Ireland, Old Man Prohibition is trying pretty hard to drive the “snakes” out of the U.S.A., but bootleggers and moonshiners see to it that “snakes” may be seen at any time by anyone who has the price.

Postponed Again — The income tax man, who has been giving us several dates for his visit here, asks us to announce that he will be here around the 18th for two or three days.

Court Postponed — The spring term of District Court which was to have convened here the latter part of this month, has been postponed to the 22nd of April.

(ibid, page 5)
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The Idaho Republican. March 17, 1920, Page 2



Another Widow Spoiled by the Pension

S. E. Roundy and family moved into Idaho and made their home. After two or three years Mr. Roundy died of influenza on October 17, 1918, at Blackfoot, and on December 7, 1918, the name of Cassie D. Roundy was placed on the county pay roll to receive a widow’s pension of $25 per month. On the 4th of September, 1919, her allowance was raised from $25 a month to $30 a month at her request because she said she needed more money to clothe the children for school.

On the 5th of December, 1919, she stated to a reporter of the Idaho Republican that she was about to be married to Moses Childs of Springville, Utah, and she introduced Mr. Childs. She further stated that she was very happy and had very bright prospects, as Mr. Childs was a fine man and owned a great deal of property. They were then on their way to be married in the Salt Lake temple, according to Mrs. Roundy, and we have no information that their plans miscarried.

Marries But Draws Pension

Mrs. Roundy’s pension warrant for November, 1919, was due to have reached her just before they started on this trip. On the 1st of January, another pension warrant for $30 was mailed to her at Blackfoot, Idaho, the pension clerk having no knowledge of her marriage and having no control over pensions, or authority to do anything but issue the warrants till the order was countermanded. The January warrant has not been returned to the auditor’s office, and the inference is that the letter containing the warrant would go as usual to the home of her relatives who live near Blackfoot, and they would forward it to her at Springville. She did not return it to the officers of this county and did not notify them of her marriage. She left no forwarding order with the postoffice at Blackfoot.

On the 1st of February, 1920, another warrant for $30 was mailed to her at Blackfoot, and it has not been returned, payment has not been declined, and she has not notified the officers of her marriage. The inference is that she is not grateful to the people of Idaho who so faithfully provided her with cash after her husband’s death, and up to the time when she married this wealthy Mr. Childs, Moses by name. The inference is that she is not only willing to accept sums under the polite name of pension while she has no income and is living with well-to-do relatives, but she is willing to keep right on accepting it after her marriage to a man, who as she says, has a great deal of property.

We Told You So

We have heretofore expressed our belief that a widow’s pension is a good thing if it could be rightly administered, and we have at various and sundry times furnished our readers with proof that it cannot be rightly administered under our present political system and with human nature constituted as it is. We have brought it to the attention of our readers that a large percentage of the widows do not look upon it as alms, but as something they have coming by reason of the fact that they have survived a husband, and it is looked upon as a triumph to receive it, rather than as something to be accepted in humility and with gratitude to the people who furnish it.

We have said before, and we repeat it, that such a large percentage of widows take these views of aid, that the act authorizing its payment ought to be repealed, because it is largely misapplied aid, and a large number of the widows who receive such aid are not such good citizens as they were before they received it. We have pointed out the fact that widows living with husbands are not eligible to receive pensions, and that many of them apply for and receive help as indigents, and them some of them spend the money for luxuries, and because we have opposed the repeated allowance of money or orders for merchandise to people who do that way, we have gained the reputation of being opposed to helping the poor. And this is partly correct inasmuch as we are opposed to helping the crooked and immoral poor. When they show their ability to expend their allowance for useful things which they need, and when they show their ability to act out consitent and moderately moral lives about like other people who have a struggle for existence, then we approve of helping them by the use of public money.

Free Like Salvation

A good many of these poor people who receive public money in one form or another, think that public money rains down from out the skies as manna did among the children of Israel, or as the water flowed because Moses tapped the rock, but recent investigations show that some of this public money is filched from the pockets of corporations, profiteers and members of the “kept press.” It has also come to light that many people pay taxes who are only well-to-do or who are owners of a great deal of property like this modern Moses of Utah whose surname is Childs.

In addition to all that, it has been found that a good many poor people pay taxes – people who have only one bread-winner in the family, and many members to be fed and clothed during these days of high cost, etc., and it makes our stingy heart bleed to know that so many dry farmers and other farmers who are not so dry, have to dig up their hard-earned money to supply money to a mixed lot of widows and near-widows, only part of whom are really in need of it. A good many people in this country have borrowed money to pay their share of the taxes, and many others are wearing their old clothes and thin underwear because it took all their money to pay the taxes. It is out of such slender purses as these that a large part of this widow’s pension money is drawn, and the editor of this little sheet again raises his voice against the law and the system that permits it.

System is Wrong

But the law will never be repealed. There is not a legislature that would have the courage to repeal it for fear somebody would say about them just what some people have said about ye editor when we have objected to the results the law brings. The average candidate is afraid to express his real opinions about such matters, and it took us ten years to repeal or modify a fool law which we call the direct primary. A candidate would be afraid of losing the votes of a hundred widows in his county even if he knew he was going to gain five hundred by declaring he would vote to repeal the law. It is easy to get laws enacted that are a mistake, but it is very difficult to get them repealed, just because of politics.

Another One Complaining

Only a few days ago a woman at Aberdeen got the probate judge on the long distance telephone and said that she had been a widow for nearly a year now and that she was not getting any pension yet. She probably thinks that is is an endurance contest and that if she waits long enough she will get hers. She seemed to be reproaching the judge because he had not boxed up some money and sent it to her as a reward of merit for outliving her husband and waiting so long without kicking up any fuss. A judge is not supposed to go out over the county sifting or advertising for persons entitled to pensions. If they are really in need they will probably make application for aid and submit their claims for consideration instead of wiring a kick to the court house because the money has not arrived before it was asked for or before the court knew she was in existence.

source: The Idaho Republican. (Blackfoot, Idaho), 17 March 1920. Chronicling America: Historic American Newspapers. Lib. of Congress.
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The Idaho Republican. March 17, 1920, Page 5

Amos Atkinson and his little daughter have been visiting a few days with Mr. Atkinson’s relatives, Mr. and Mrs. O. W. Bills. Mr. Atkinson married Mrs. Bills’ sister, Miss Pope, tend years ago, and she died of influenza about six weeks ago.

(ibid, page 5)
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The Idaho Republican. March 17, 1920, Page 3

Local News

Miss Jenny Hymas was called to Bear Lake, Utah, Sunday on account of the illness of her mother.
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An opening dance was held in the Ensign hall last Saturday evening. This being the first regular Saturday night dance held in the hall for about two months. A fairly good sized crowd was in attendance and a good dance was enjoyed again by all present. The Hansen orchestra furnished some snappy music, playing the latest dance pieces.
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To the relatives of each man who died overseas the Red Cross is sending a photograph of the grave.

(ibid, page 11)
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The Idaho Republican. March 17, 1920, Page 4

Willie Sequetsie, Indian Cowboy, Dies

Willie Sequetsie, a fine indian cowboy, about twenty-one years of age, died at his parents’ home last Friday, March 12, after suffering with an illness for many weeks that weakened him and left him too frail to keep up the fight against death.

His father is Jimmie Sequetsie and the young man was a grandson of the old Indian scout, Jack Hurley.

Willie was a familiar figure in Blackfoot during a day or season of sports when the Indian cowboys are so much appreciated by their white friends. Willie had a good education that helped him greatly in making him a big asset to his own people. One of his brothers, Tommy, is being educated in the Blackfoot schools this term, being enrolled at the Irving. The remains of the young man were buried at the Mission house Monday, in charge of Mr. Wagner.

(ibid, page 12)
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Pythian Castle, Kinghts of Pythias, Weiser, Idaho ca. 1911 (1)


Photo courtesy: the Mike Fritz Collection, History of Idaho
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March 18

The Emmett Index. March 18, 1920, Page 1


St. Patrick’s Dance a Success

The American Legion’s St. Patrick’s Day ball last evening was largely attended and was a grand success. The ball was gay with green and white decorations, and the floor was taxed to its capacity to accommodate the large number of dancers.
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Mrs. Samantha Phillips died Sunday night of pneumonia at her rooms in the Colonial rooming house. Mrs. Phillips was the mother of Mrs. S. T. Johnson of the bench, and with her son Henry came from Fruita, Colo., about ten weeks ago. She was a member of the Mormon church and 62 years old. A short service was held at the Bucknum chapel yesterday afternoon, and the body, accompanied by Henry Phillips and Mrs. Johnson, was taken to Fruita, Colo., for burial beside the husband who had preceded her in death.

source: The Emmett Index. (Emmett, Idaho), 18 March 1920. Chronicling America: Historic American Newspapers. Lib. of Congress.
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The Emmett Index. March 18, 1920, Page 3


(Too late for last week)

Springtime is coming gentle Annie, and fencing is the order of the day.

Mrs. W. F. Rose is on the sick list this week having taken a relapse after the flu.

Mother Whitlock went to Emmett last Saturday with her little grandson, who will be under the doctor’s care for a while.

Mr. and Mrs. L. S. Park are able to be out again after a two weeks siege with the flu.

Mr. Beach, who had been working at the logging camp in Round Valley, came home sick last week. He died later.

(ibid, page 3)
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The Emmett Index. March 18, 1920, Page 4

Red Cross Annual Report

We, the undersigned, auditing committee of Gem County Chapter The American Red Cross, have examined and audited the books and records of said chapter, covering the fiscal year ending June 30, 1919, and from such examination and audit we report as follows:


Total received from memberships … $2829.85 …


… Nursing influenza … $8.00 …
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Died — Mr. A. W. Beach died Thursday, March 11th from a complication of diseases following the flu. Altila W. Beach was born in Wisconsin, March 26, 1861, was married at Blackwell, Colo., in 1887. He is survived by his wife Mrs. Maud Beach, two brothers and one sister. They are Marion Beach of Cannon City, Colo., Orn Beach of Netherlands, Colo., and Mrs. Olive Bingham of Calahan, Calif.

Mrs. W. F. Rose is quite sick at this writing.

The way people are fencing, it begins to look like the outside range is a thing of the past.
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Is Having Great Time

Will McCall went down to Boise some time ago for a little vacation, and had a slight nasal operation performed. Then he got the flu. After he got on his feet he had his tonsils removed, and now he’s in the hospital with the small pox. He is having a great time, and expects to be home as soon as he has the measles and the mumps and appendicitis and a few more things running loose in Boise the Beautiful. — McCall Star
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The Future Newspaper

The newspaper office of the future, according to Oscar Roesen, vice president of R. Hoe & Son, press builders, will be one without presses, casting boxes, typesetting machines or any of the other machines so common in a newspaper office today. His prediction is that a newspaper office will be composed of a large room filled with telegraph instruments and operators, each instrument connected with thousands of wires forming a cable running under ground to the houses of all subscribers, with a stock ticker printing arrangement connected by a wire with the main instrument in the publication office. Before the subscribers goes to bed he puts in a fresh sheet of paper, and while he sleeps the news is printed on the sheet and read at his breakfast. Some service.

(ibid, page 4)
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The Emmett Index. March 18, 1920, Page 5

[Emmett News]

W. T. Crouch is confined at home this week by illness.

W. T. Crouch was able to be up town today, after being sick at his home the past few weeks.

The mother of Mrs. J. C. Loyd is critically ill and her children from distant parts have come to be at her bedside.

C. A. Whitman is confined to his home by sickness.

John Burger, who has been ill for two weeks, was taken to a Boise hospital on Sunday for treatment.

Mrs. Ray Stinson underwent a serious operation in a Boise hospital on Monday. Late reports state that she is improving slowly.

F. N. Luse came over from Nampa on Monday and took back with him that afternoon his wife, who has been very ill at the home of her brother R. B. Shaw in this city. Mrs. Luse is suffering from a stroke of paralysis and is in a serious condition.

Dr. W. E. Allen was taken to Boise yesterday to consult osteopathic physicians who are in attendance at a clinic from Los Angeles and other cities. Dr. Allen has not been improving as well as had been hoped, and will remain there for treatment.

Mrs. Robert Holbrook left Monday for California to bring her parents, Mr. and Mrs. S. A. Wells home. Mrs. Wells health has been very poor.

Jerry Boren returned Sunday from Texas, where he was called by the illness of his mother. He left her improved and indications are for a recovery.

Miss Grace Exum passed thru Emmett from Boise Saturday enroute to McCall, where she goes to take a position as stenographer in the U. S. Forestry office. Miss Exum is one of our High school graduates who is making good.

(ibid, page 5)
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The Emmett Index. March 18, 1920, Page 10

News Of Gem County
By The Index’s Correspondents

South Slope

There are some thirty teams at work on the Canyon canal in the vicinity of Rocky Point, carrying their work forward in fine shape to meet the line of teams from Ray Stinson’s camp working down from Picket corral hill. All indications point to early water in this canal and plenty of it.


Leu Idle is very ill at his home with the mumps. Mrs. McMurran is caring for him.

Mrs. F. L. Palmer, who has been ill for several weeks, is slowly improving.

Mrs. H. A. Gatfield received a phone from Dr. Montgomery of Caldwell Tuesday, stating that Harry was improving and would be able to leave the hospital in a few days.

Bissell Creek

Dr. Harry Smith has been real ill the past week.

Thos. Slone is still pretty sick with the mumps.

Mr. and Mrs. Walter Craig attended the funeral of Clem Dunn Thursday.

The spring plowing here is in full swing.


Mrs. R. L. Battan was quite ill the least of the week, but is on the road to recovery at this writing.

Mrs. Bayston, county superintendent, visited the Letha school Tuesday morning.

H. C. Riggs met with a painful accident Tuesday when he was working with a fresno. His ankle was dislocated and the tendons of the leg twisted and a small bone broken. He will be laid up some time.

Jim Butler helped Ed Bott carry Mr. Riggs to the house the day he was hurt. His army experience, carrying wounded men, made it easy to pack him with the least possible pain.

Central Mesa

The box social at the Central Mesa school has been postponed on account of sickness.


Master Phillip Carter is a recent victim of mumps.

The little daughter of Mr. and Mrs. Jack Norwood is reported to be improving, which is welcome news to their many anxious friends.

Mrs. Samantha Phillips, mother of Mrs. S. T. Johnson, died in Emmett Sunday night of pneumonia. The body was taken to Fruita, Colo., for burial.

(ibid, page 10)
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The Wallace Miner. March 18, 1920, Page 6


19200318WM2Drinking Water in Mines

The drinking water used by miners underground is of as much importance as that in use on the surface. The water used for drinking purposes underground should be free from filth or contamination. Many diseases are spread in this manner, among which are common colds, influenza, pneumonia and syphilis. Where drinking water is piped underground a simple sanitary device may be arranged by means of a pipe with a union on the end too big to be placed in the mouth. It is better so to place this union on the end of the pipe that the water will not come in an upright stream, but pour out on the side.

source: The Wallace Miner. (Wallace, Idaho), 18 March 1920. Chronicling America: Historic American Newspapers. Lib. of Congress.
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Idaho County Free Press. March 18, 1920, Page 1


19200318ICFP2Cecil Johnson Is Dead At Age Of 16

Cecil Johnson, 16-year-old son of Mr. and Mrs. James Johnson, residing ten miles north of Grangeville, died Thursday morning as a result of complications following scarlet fever and influenza.

He is survived by his parents, five brothers and one sister.

The funeral will be held Sunday from the Zion church, Winona. A. J. Maugg, of Grangeville will direct the funeral.
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Throngs At Dance

What perhaps was the largest crowd to attend a dance in Grangeville in many months was present at the overall and apron dance given the evening of St. Patrick’s day, by Neighbors of Woodcraft, in I.O.O.F. hall.
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C. B. Knorr, 77, And Mrs. Julia Garber, 73, Wed

Stealing a march on their friends, C. B. Knorr, 77 years old, and Mrs. Julia Garber, 73, hied their way to Lewiston Wednesday morning, where they were married. The “young” couple left for a honeymoon, which will include a visit to Portland, and possibly California.

The bride and bridegroom are pioneer residents of Idaho county and had known each other for years. Close friends of the couple, however, were much surprised, when they learned, on Wednesday, that the years of friendship had culminated in a romance which led to the alter.

Mr. and Mrs. Knorr, following their wedding tour, will reside in Grangeville.

source: Idaho County Free Press. (Grangeville, Idaho), 18 March 1920. Chronicling America: Historic American Newspapers. Lib. of Congress.
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Idaho County Free Press. March 18, 1920, Page 2


(Special Correspondence)

Ethelyn Zerr, Dorothy Chamberlin and Lloyd Mahurin, were severely ill last week, but are recovering.

Harry Zerr of Whitebird made a business trip to Grangeville, returning home Saturday. He went outside on horseback, owing to bad roads. As this was his first horse back ride in twenty-five years, Harry was compelled to secure first aid in the shape of a team and buggy to bring him home.

Contractor William Campbell of Grangeville has started repairing that part of the school house which was washed away by the flood a few years ago. Part of the old building will be removed and the remainder will be remodeled by the use of cement blocks.

Mr. Granger of Grant Smith & Co., Camp 3, was badly injured last week while uncovering a blast. Three kegs of powder had been placed in the hole but were covered by a landslide before the powder could be exploded. Mr. Granger was engaged in removing the dirt when a spark touched the powder, causing it to explode. He incurred many cuts about the head, while a helper who was blown about twenty feet in the air, escaped injury. Dr. W. A. Foskett was summoned to care for Mr. Granger.

(ibid, page 2)
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The Nezperce Herald., March 18, 1920, Page 1


Postpone Court Till May – Judge Scales Ill.

[Act]ing on the advice of his physician, Judge W. N. Scales, who … of influenza, yesterday notified ? L. Schnell, clerk of the … court, that the Lewis … term of court, which was … March 22, would be postponed … to May 31.

… is the regular February .. of court, which had been adjourned from February 2, last, to March 22 on account of the influenza quarantine which was in effect in this county. The … to date, shows only a … small nunber of … however, and it is likely … will still be a light one … held in May.

… Judge’s many Lewis county friends will be glad to know … his influenza attack is of the mild form, but owing to the serious nature of the malady, …doctor advised against any … until he was entirely …

[side of page unreadable]
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Local News

Assessor E. H. Ratliff has been confined to his bed the past several days by a severe attack of stomach ailment.
— —

Morrowtown News

Wm. Cooper is seriously ill with the flu.

John Cooper is under the physician’s care.

As The Herald goes to press the word comes that Evert Beenders is extremely low from complications following the flu and little hope is entertained for his recovery, which news is sadly received by the community, for everyone holds in high esteem this fine young man.

Mail Carrier Johnson came in every other day this week, owing to the bad roads.

source: The Nezperce Herald. (Nezperce, Idaho), 18 March 1920. Chronicling America: Historic American Newspapers. Lib. of Congress.
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The Nezperce Herald., March 18, 1920, Page 2

Central Ridge News

Dr. Horswell, of Orofino, was called to the Ridge Tuesday.

Nando Thomas’s daughter, Viola, is ill.

(ibid, page 2)
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The Nezperce Herald., March 18, 1920, Page 7

Local and Personal News Notes

Evert Beenders, one of our best known and most highly esteemed young farmers, is very ill at the Cook home in this city of a complication of bronchitis and stomach trouble, following an attack of influenza. His case became serious last night and no improvement is apparent this afternoon.

The son born to Mr. and Mrs. R. E. Moser last Friday, died yesterday morning. Mrs. Moser, whose condition was critical following the ordeal, is said to be much improved.

The Red Cross is sending to the relatives of each man who died overseas a photograph of his grave.

(ibid, page 7)
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Josephine Hospital, Weiser, Idaho


Photo courtesy: the Mike Fritz Collection, History of Idaho
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March 19

The Rathdrum Tribune., March 19, 1920, Page 1


Only Routine Work Transacted By Town Board Tuesday Night

Owing to the presence of but a quorum, the village trustees considered only routine matters at the adjourned meeting Tuesday night. Bills were allowed to the amount of $245.65. Of this sum, $67.50 was for the recent digging out, thawing with fire and repairing of a stretch of frozen water main in the south part of town. The pipe froze in February and the expense was incurred to restore service to three homes.

The clerk was instructed to publish a notice that unlicensed dogs running at large after March 29 will be impounded and 50c penalty added to the license to redeem them, and that owners can save the said penalty by paying the regular license before that date.

The marshal reported only one home quarantined with influenza, all others having been released.

Action on the proposed water bond issue, the appointment of a new trustee to fill the vacancy on the board, and some other matters was deferred.

Bills allowed:
W. H. Cleland, pole wood for thawing pipe … $5
R. C. Hite labor thawing pipe … 36
Cecil Feoreto ” ” … 2
A. T. Gaston ” ” … 7
C. E. Powell ” ” … 7.50
S. Beck labor and material repairing frozen water main … 10
Geo. W. Flemming, marshal … 81
Rathdrum Ele. Co. Feb light … 79.50
F. G. Hart salary as bandmaster month of Feb. … 10
J. R. M. Culp, paid for dog tags and phone tolls … 3.65
E. W. Cady, marshal Feb. 29 … 4
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From Over The County

Post Falls

The Post Falls water company is complying with an order of the public utilities commission to repair and improve the system within 60 days.


The W. H. Bartells residence was destroyed by fire the night of March 7, and several neighboring buildings were saved only by prompt and hard work. The Y.M.C.A. building was damaged and the hospital buildings were threatened.

No services have been held lately in the Methodist church, the church being without a pastor.

Spirit Lake

The working people of Spirit Lake want the daylight saving time schedule restored.

Coeur d’Alene

Percide Secaur, age 23, wife of Albert Secaur, died Saturday night of pneumonia, following an attack of influenza. The deceased leaves a husband and two children.

A 20 per cent increase in the county school tax levy was recommended by the school trustees of Kootenai county at their annual meeting. The increase was declared necessary to meet the advance in teachers’ salaries. It was pointed out that this would mean an increase of only 10 per cent in the total school revenue, as only about one-half of the school funds have heretofore been raised by the county levy.
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Idaho State News Items

Idaho school children are being asked to give one penny each for “America’s Gift to France,” a statue to be erected by Americans on the battlefield of the Marne. Ethel E. Redfield, state superintendent of public instruction, notified county superintendents that the week of March 22-27 as been set aside for making such gifts.

Idaho’s share of the $257,000,000 federal appropriation for road building in 1920-21 is $1,159,967

In the 12 months ended November 1, 1919, 1503 men were injured in the timber industry in Idaho, and 807 in mining and quarrying.

Lumbering is Idaho’s most dangerous industry. Mining ranks second. Thirty years is the workingman’s most reckless age. Most injuries in Idaho come from falling, rolling or flying objects (stones, logs, pieces of machinery, etc.); and hands and feet are the members most often injured. These are interesting facts gleaned from an annual report submitted to Governor Davis last week by the industrial accident board of Idaho.
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World News In Brief

The American Legion now has a membership of more than a million in 8475 posts.

A proposition is before the U.S. congress to vote a cash bonus to ex-service men of $50 for each month served. It is estimated the proposed bonus would necessitate the expenditure of two and a half billion dollars.

The United States has an army of 13,000 men under General Allen in the sphere of occupation in the Rhineland. The force is entirely motorized and ready to do its part in enforcing the armistice terms on Germany.

Herbert Hoover testifying before the senate committee investigating the navy department’s conduct of the war, on March 13 expressed the belief that American participation turned the scales in favor of the allies at the critical period of the war, although it was incorrect to say that the United States won the war.

source: The Rathdrum Tribune. (Rathdrum, Idaho), 19 March 1920. Chronicling America: Historic American Newspapers. Lib. of Congress.
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The Rathdrum Tribune., March 19, 1920, Page 3

Personal Mention

J. J. Bradbury was in town yesterday for the first time since recovering from the flu. Eight of the family, including Rudolph Myer, were ill at the same time. Mr. Bradbury has gotten behind in his efforts to keep his customers supplied with wood but expects to be at it again as soon as he is able.

W. S. Gill was taken to Spokane yesterday morning for an operation to prevent recurrence of hemorrhages from the head. Mr. Gill has been in poor health all winter and recently suffered a severe attack of influenza.

C. B. Sanders, who had the misfortune to cut his arm so badly while operating a wood saw last week, is reported doing as well as could be expected by friends who call to see him in the hospital in Spokane.

Elmo Morris, who came home from Connell, Wash., several days ago suffering with appendicitis, went to Spokane Wednesday for an operation which had been deferred on account of the overcrowded condition of the hospitals.
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Local Paragraphs

The local Red Cross branch wishes all persons who have discarded clothing or shoes to turn same into the Rest room for benefit of local service work. The Red Cross officers desire a good attendance of members at the regular meeting on Tuesday, March 23, at the Rest room.

(ibid, page 3)
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The Oakley Herald. March 19, 1920, Page 8


In the Gem State

Dr. L. C. Henderson, state veterinarian, is conferring with stockmen regarding the hog cholera situation in the southern part of the state. Last fall the disease gained quite a start, but was finally put under control and the state veterinary department has been keeping close watch on it since.

The expansion of ice on Payette lake has caused the lake to swell. Because of the shoreward movement of ice, piles driven near the edge of the lake have been tilted to an angle of 45 degrees and wharves and buildings along the lake have been damaged.

Montpelier is now in line for free delivery of mail, and the Boosters club has taken up the proposition of naming the streets and numbering the homes.

Lewiston has appointed a motorcycle policeman who will patrol the main streets of the city with the duty of enforcing the city traffic and speed ordinances.

source: The Oakley Herald. (Oakley, Idaho), 19 March 1920. Chronicling America: Historic American Newspapers. Lib. of Congress.
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Clearwater Republican. March 19, 1920, Page 1


Four Die During Past Week

Mrs. Marilla Keller, aged 83, died of old age here Saturday night, March 13th, at the home of her nephew, Harry L. Walrath. …

Elmer Hibbeln, aged 44, died at his home just south of Orofino, Friday night, March 13th after several day’s illness from pneumonia. He had been in the employ of the Crustaline Lime Company, working night shift in the tunnel being sunk into the company’s holdings here. He was born in Wisconsin February 7th, 1876, and was a laborer by vocation. He is survived by a widow and six children, the eldest son, Lawrence, being in the navy and stationed at San Francisco and just recovering from the influenza. The funeral was held Sunday from St. Joseph’s church, the Rev. Father Couffrant conducting the services.

Amelia Wheeler, the 11 year old daughter of Mr. and Mrs. Sam Wheeler of the Grangemont section, died Saturday March 13th from cerebral meningitis, while enroute to Orofino for medical treatment. Burial took place Monday in the Sanders cemetery on Eureka Ridge.

Mrs. Elizabeth Farris, aged 74, died at the Northern Idaho Sanitarium March 9th from artery sclerosis. She was committed to the sanitarium March 3, 1920, from Coeur d’Alene …
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Card of Thanks

We wish to sincerely thank all friends and neighbors who kindly assisted us in our bereavement of our aunt, Mrs. Armilla Keller.

H. L. Walrath and family

source: Clearwater Republican. (Orofino, Idaho), 19 March 1920. Chronicling America: Historic American Newspapers. Lib. of Congress.
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Clearwater Republican. March 19, 1920, Page 2

Recent Deaths

Spokane — Death claimed Saturday two of the oldest inhabitants of the city. Both were more than 100 years old.

Thomas Street, who would have been 101 on his next birthday, March 21, died at his home W3518 Hoffman avenue. His daughter, Mrs. Jennie Schiedegger, died of influenza Jan. 31, and Mrs. Schiedegger’s daughter, Mrs. Anna Sharp, died Feb. 11 of the same disease. It was the grief caused by their deaths which was the beginning of the end. He was stricken with a form of apoplexy two days before he died.

The other centenarian’s death was that of Samuel Merritt. Mr. Merritt was 100 years old January 18 when he entertained a large number of his friends. Mr. Merritt was a member of Reno post, G.A.R., came to Spokane from Topeka, Kan., in 1902, and has made his home with his daughter, Mrs. E. F. Boyles.
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Fighting The “Flu” In Chicago
This picture shows a doctor in the city laboratories preparing the anti-toxin for Chicago patients who are suffering with the influenza.
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Summary Of The World’s Events

Hope has been abandoned in Paris for a Russian steamer chartered by the American Red Cross, which left Novo Rossisk on the Russian east coast of the Black sea, for Constantinople with 500 wounded and sick refugees.

(ibid, page 2)
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Clearwater Republican. March 19, 1920, Page 5

What Your Friends And Neighbors Are Doing

I. R. Crow, publisher of the Orofino Tribune, has been confined to his bed this week with an attack of the “Flu.” He took ill last Friday and was unable to publish the Tribune until Wednesday afternoon. At this writing he is reported to be rapidly improving.

Charley McNew, son of W. M. McNew, of Eureka Ridge, almost severed the thumb of his left hand while splitting wood at home, on Thursday evening. Dr. Horswill and Fairly attended the young man in Dr. Horsewill’s office and rendered the required surgical aid. It was necessary to place the boy under the influence of ether to put in several stitches. The bone of the thumb was not entirely severed but a tendon was cut which Dr. Horswill hopes to unite.
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(ibid, page 5)

Further Reading

Idaho Vaccination Clinic


This photo of a Depression-era outdoor vaccination clinic was taken at an unidentified location in Idaho.

source: National Laboratory of Medicine via ID AHGP
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The State of Science, Microbiology, and Vaccines Circa 1918

John M. Eyler, PhD US National Library of Medicine – National Institutes of Health


The influenza pandemic of 1918–1919 dramatically altered biomedical knowledge of the disease. At its onset, the foundation of scientific knowledge was information collected during the previous major pandemic of 1889–1890. The work of Otto Leichtenstern, first published in 1896, described the major epidemiological and pathological features of pandemic influenza and was cited extensively over the next two decades. Richard Pfeiffer announced in 1892 and 1893 that he had discovered influenza’s cause. Pfeiffer’s bacillus (Bacillus influenzae) was a major focus of attention and some controversy between 1892 and 1920. The role this organism or these organisms played in influenza dominated medical discussion during the great pandemic.

Many vaccines were developed and used during the 1918–1919 pandemic. The medical literature was full of contradictory claims of their success; there was apparently no consensus on how to judge the reported results of these vaccine trials. The result of the vaccine controversy was both a further waning of confidence in Pfeiffer’s bacillus as the agent of influenza and the emergence of an early set of criteria for valid vaccine trials.

When the great influenza pandemic of 1918–1919 began, the most important sources of knowledge about epidemic influenza were studies conducted during and immediately following the previous pandemic, that of 1889–1990. The 1889–1890 influenza pandemic was the first to occur in the Western world after the pandemic of 1848–1849. That meant that it was the first to have taken place since more prosperous nation states had created active, professional health departments and systems of vital statistics, and the first to be studied using the methods of modern pathology and bacteriology. The 1889–1890 pandemic generated a very large literary output and two particularly important biomedical syntheses. In 1891, Franklin Parsons, a member of the Medical Department of the Local Government Board in London, published a 300-page report on the pandemic based on surveys of all sanitary districts in England and Wales and on local studies in selected areas. Five years later, drawing on continental, especially German, scientific and clinical literature, Otto Leichtenstern published the definitive scientific study of influenza in Hermann Northnagel’s multi-volume handbook of special pathology. These two major works, particularly Leichtenstern’s, were the well from which American authors of medical textbooks and reference works, such as William Osler and Frederick Lord, would draw for the next two decades and the standards against which medical authorities would judge their observations and conclusions during the next great pandemic.

It says volumes about the rudimentary state of scientific knowledge of influenza in the early 1890s that the most important and lasting conclusion of these two seminal works was that influenza was a specific, communicable disease. It did spread very rapidly, more rapidly than any other known communicable disease, and it produced explosive local outbreaks. However, it never arose spontaneously, nor did it travel faster than humans travel. Close investigation easily debunked accounts of outbreaks occurring without precursor cases or in places without contact with infected individuals. Furthermore, isolated populations, such as those within prisons in heavily infected cities, sometimes escaped entirely. Although influenza occurred more often in winter and spring months, the pandemic struck in all latitudes of both hemispheres, at all altitudes inhabited by humans, and in all climates. It was clearly not caused by overt climatic or environmental factors. A serious influenza epidemic was seldom a solo event. A major epidemic was often followed within months by one or more additional outbreaks. Authorities of the early 1890s recognized that the diagnosis of influenza was difficult, and that mild cases were easily confused with other respiratory and catarrh-like disorders. They were quite certain from clinical and epidemiological records that the influenza of the great pandemic of 1889–1890 was the same disease that had caused the influenza pandemics of the past, such as that of 1848–1849. The more vexing problem was whether this pandemic influenza was the same disease as the disorder commonly known as influenza or grippe that occurred almost every year. Parsons thought they undoubtedly were distinct diseases; Leichtenstern agreed, although less adamantly.

Influenza Types

Its clinical features and its opaque identity made influenza seem an especially protean disease. Writing in 1907, Clifford Allbutt, Regius Professor of Medicine, “observed influenza is of protean diseases the most protean; more diversified even than syphilis.” Individual cases were characterized by their sudden onset and by extreme prostration, which was out of all proportion to other pathological features. The disease’s regular target was the respiratory tract, and pneumonia was the most serious complication of influenza and the major cause of mortality during an outbreak. But Leichtenstern observed that cases might exhibit no respiratory symptoms at all. In addition to the typical respiratory cases, both he and Parsons passed on a division of three subtypes inherited from earlier authors: nervous, catarrhal, and gastric. In succeeding years, the number of recognized clinical types swelled enormously. In 1907, when Frederick Lord wrote his chapter on influenza in Osler’s multi-volume reference work, Modern Medicine, he described no fewer than 10 clinical types, including influenza of the circulatory system, of the genito-urinary system, of the joints, and of the skin. Influenza, it seems, was having an identity crisis. This is a point to which we will return.

The generation working after the pandemic of 1889–1890 also classified influenza cases according to their occurrence and presumed cause. Leichtenstern proposed a tripartite division of influenza types: pandemic influenza vera (the disease that occurred in great global outbreaks), endemic-epidemic influenza vera (the disease having the same cause but which occurred in smaller outbreaks following a pandemic), and endemic influenza nostras (pseudo-influenza due to different causes). Both Osler and Lord passed on this classification to their readers, although Lord significantly altered the third category to endemic influenza vera, suggesting that cases in this classification must have the same cause as those occurring in epidemics.

The experience with the 1889–1890 pandemic taught medical authorities that pandemic influenza was a disease of very high morbidity and low case fatality, although it seemed that in the outbreaks immediately following a pandemic, morbidity rates could be expected to decline and case fatality rates to rise. Given the problems of differential diagnosis and the existence of mild cases, exact statistics were difficult to obtain. Authorities concluded, however, that in 1889–1890 the infection was very widely distributed in European nations. Leichtenstern estimated that as much as 50% of the German population had been infected, while Parsons put the estimate for Greater London at 25%. Reported incidence rates for employees of British institutions ranged from 9% for troops stationed in Britain to 33% for postal employees.

The experience of 1889–1890 suggested that pandemic influenza had distinct patterns of age-specific morbidity and mortality. Continental figures indicated that morbidity was highest between ages 20 and 40 and lowest after age 50, while case fatality rates were highest among the elderly. Deaths registered as due to influenza in England and Wales were highest in the age group 40–60 at 36%, while 24% of influenza deaths took place between the ages of 20 and 40 and 22% between the ages of 60 and 80. Parsons demonstrated that this mortality pattern was very different from that of the inter-pandemic period. Between 1876 and 1889, 33% of deaths attributed to influenza occurred in the first year of life and another 34% occurred after age 60.

The Bacteriology Of Influenza

During the pandemic of 1889–1890, researchers used the new methods of medical microbiology in unsuccessful efforts to identify the microbial cause of influenza. An apparent breakthrough came in 1892, during a subsequent outbreak, when Richard Pfeiffer announced in a single-page preliminary publication, and a year later in a more substantial article, that he had found influenza’s cause. Pfeiffer reported finding in every case of influenza he examined a rod-shaped organism. In uncomplicated cases he found these bacilli in overwhelming numbers and frequently in pure culture. Pfeiffer’s bacillus was challenging to work with. It was very small and fastidious. It would only grow on blood argar plates. It could not be stained with Gram’s stain, but it would accept Loeffler’s methylene blue stain, and it displayed characteristic polar staining, making it easy to confuse with diplococci. Pfeiffer was never able to find an animal model for influenza, although he innoculated mice, rats, guinea pigs, rabbits, pigs, cats, dogs, and monkeys. To further complicate matters, although he had focused his investigation almost exclusively on influenza cases, he reported finding in a few cases of “diphtheric bronchopneumonia” a bacillus that was indistinguishable from his own bacillus on the grounds of morphology and of culture and staining characteristics. He labeled this organism pseudo-influenza bacillus.

In retrospect, Pfeiffer’s chain of evidence may seem more shaky than it did to his contemporaries. Pfeiffer, a protege of Robert Koch, was, after all, a productive and distinguished bacteriologist. Contemporaries respected the technical skill he exhibited in isolating and characterizing his bacillus. The failure to satisfy Koch’s Postulates by producing an experimental disease in animals by the inoculation of pure culture was not in itself damning. Koch, himself, had sometimes failed in this regard. The existence of the pseudo-influenza bacillus would seem to his contemporaries no more implausible than the existence of the pseudo-diphtheria bacillus. While the scientific response to Pfeiffer’s discovery is difficult to characterize concisely, it does seem fair to conclude that most medical authorities believed that Pfeiffer was basically correct in his identification, even though his evidence might not be complete. (Although the organism that Pfeiffer isolated was most likely what we know today as Hemophilus influenzae, we refer to it in this article in the way it was referred to during the period under discussion: Pfeiffer’s bacillus and Bacillus influenzae [B. influenzae]).

Parsons published before Pfeiffer’s announcement, but Leichtenstern published three years after, and he endorsed Pfeiffer’s discovery with only modest qualification. “Should the Bacillus influenzae, discovered by R. Pfeiffer in 1892, continue to maintain in future pandemics its place as the exclusive cause of the disease, as may certainly be expected, its discovery may be considered as the most important achievement of our latest influenza pandemic.”

In succeeding years there was keen interest in Pfeiffer’s bacillus. In 1892, when Pfeiffer announced the discovery of B. influenzae, Americans had little, if anything, to add to the discussion. By 1918, on the other hand, they were active participants. By that time, laboratory courses in medical bacteriology were being taught in most American medical schools, diagnostic laboratories operated in many hospitals and in some public health departments, and in some laboratories American bacteriologists were already doing world-class research. The active participation of medical officers in the U.S. Army in 1918 and 1919 is an indication of how widely disseminated the new laboratory techniques were in the American medical profession. These laboratories may seem rudimentary by 21st century standards. Microorganisms were identified primarily by morphology and by basic culture and staining techniques. Routine clinical diagnosis, sputum examinations for tuberculosis, and throat cultures for diphtheria, for example, had begun to exploit these basic laboratory techniques. More specialized techniques, such as the Widal examination of typhoid fever and complement fixation tests such as the Wassermann test for syphilis, were early examples of the exploitation of immunological phenomena. Filterable viruses were known to exist, but very little was known about them, and there were very few techniques for working with them.

In the years immediately following Pfeiffer’s discovery, many investigators confirmed his findings by isolating his bacillus from influenza cases. But there were complications. Others reported isolating organisms indistinguishable by contemporary laboratory methods from B. influenzae from other diseases and even from normal throats. For example David J. Davis, from the Memorial Institute for Infectious Diseases in Chicago, reported in 1906 isolating Pfeiffer’s bacilli from all but five of the series of 61 cases of whooping cough he studied. He also found them in 40% to 80% of a smaller number of cases of cerebro-spinal meningitis, varicella, measles, and bronchitis. Significantly, he succeeded in isolating Pfeiffer’s bacilli in only three (18%) of 17 cases of influenza.

Such results suggested to some that Pfeiffer’s bacillus was merely a secondary invader. But these findings might also indicate that this organism was a key player in a more complex etiology. W. D’Este Emery, clinical pathologist at King’s College Hospital, London, drew attention to the fact that B. influenzae grew more readily in culture in the presence of other organisms and seemed to be more virulent for animals in the presence of killed streptococci. Emery wondered whether Pfeiffer’s bacillus might be a “harmless saprophyte” most of the time but be capable in the presence of other pathogens of being transformed into “the pathogenic bacillus which occurred in the pandemic of the nineties.”

The confusion over the etiology of influenza on the eve of the pandemic of 1918–1919 is well illustrated in the eighth edition of Osler’s textbook of 1912. In the definition of the disease he states that “a special organism, Bacillus influenzae, is found,” and in the section on bacteriology he also states that this organism “is recognized as the cause of the disease,” but he also points out that it is commonly found in other diseases and is “probably constantly with us.” Despite such reservations, medical authorities recognized that Pfeiffer’s bacillus was the only viable candidate for the cause of influenza. On the eve of the pandemic of 1918–1919, it was deeply implicated in the understanding and even the definition of the disease. That great expansion in clinical types of influenza identified in Frederick Lord’s synthesis of scientific knowledge was made possible because B. influenzae had been isolated from the blood, from heart valves, from the joints, and from the urinary tract. In an age when etiological definitions of disease were of growing importance and bacteriology was beginning to provide the gold standard for differential diagnosis in infectious diseases, Pfeiffer’s bacillus had become indispensable.

Influenza Vaccines

The fate of Pfeiffer’s bacillus as the probable cause of influenza is reflected in the use of vaccines in the United States during the pandemic of 1918–1919. By 1918, the successful use of some vaccines, especially those against rabies, typhoid fever, and diphtheria, as well as the use of diphtheria anti-toxin, had raised high expectations for a vaccine against influenza. Those who already had a vaccine in hand were quick off the mark to promote their vaccines as sure preventives or cures for influenza. Drug manufacturers aggressively promoted their stock vaccines for colds, grippe, and flu. These vaccines were of undisclosed composition. As public anxiety and demand swelled, there were complaints of price gouging and kickbacks. Preexisting vaccines of undisclosed composition were also endorsed by physicians such as M.J. Exner, who actively promoted in newspaper interviews and testimonials the vaccine developed some six years earlier by his colleague, Ellis Bonime. Bonime was a late champion of the tuberculin treatment of tuberculosis and an adherent of the opsonin theory of immune response and of the therapeutic use of vaccines. His vaccine was claimed to prevent pneumonia, influenza, and blood poisoning. Exner’s boosterism paid some dividends. At least one municipality, Far Rockaway, New York, announced that it would provide Bonime’s vaccine to all its citizens.

Early in the pandemic, more highly respected and well-placed authorities developed vaccines based explicitly on Pfeiffer’s bacillus. On October 2, 1918, Royal S. Copeland, Health Commissioner of New York City, sought to reassure citizens that help was on the way, because the director of the Health Department’s laboratories, William H. Park, was developing a vaccine that would offer protection against this dreaded disease. Park’s successes in combating diphtheria with anti-toxins and vaccines developed in these same laboratories gave Copeland’s announcement much weight. Park explained to his colleagues that he and his staff consistently had been able to isolate Pfeiffer’s bacillus from influenza cases, and that his laboratory had isolated the current strain, shown that animals injected with it developed specific antibodies, and developed a heat-killed vaccine that was to be administered in three doses at two-day intervals.

Park’s was not the only Pfeiffer’s bacillus influenza vaccine to make an early appearance during the pandemic. At Tufts Medical School in Boston, Timothy Leary, professor of bacteriology and pathology, developed another Pfeiffer’s bacillus vaccine. His was developed from three locally isolated strains, and it was heat-killed and chemically treated. Leary promoted his vaccine as both a preventive and a treatment for influenza. Other Pfeiffer’s bacillus vaccines soon followed. Faculty from the Medical School of the University of Pittsburgh isolated 13 strains of the Pfeiffer’s bacillus and produced a vaccine from them by modifying the techniques Park had used. In the crisis atmosphere of the pandemic, the Pittsburgh vaccine developers isolated their strains, prepared the vaccine, tested it for toxicity in some laboratory animals and in two humans, and turned it over to the Red Cross for use in humans — all in one week. In New Orleans, Charles W. Duval and William H. Harris from Tulane University’s Department of Pathology and Bacteriology developed their own chemically killed Pfeiffer’s bacillus vaccine. Their justification for its use was the common presence of the bacillus in influenza cases and the example of the typhoid vaccine whose administration schedule they followed.

It was not only heads of bacteriological laboratories who acted on the assumption that Pfeiffer’s bacillus was the cause of influenza and developed vaccines on that assumption. Some private physicians did the same. Horace Greeley of Brooklyn, New York, reported isolating 17 strains of the bacillus from 17 patients, and from these “strains,” he developed a heat-killed vaccine intended to be administered in three increasing doses. With it he immunized his own patients, and he distributed eight liters to colleagues who did the same.

These vaccines were widely used. Park’s vaccine was released to the military for use in Army camps as well as to private physicians. It was also used as corporate policy among industrial workers, including the 14,000 employees of the Consolidated Gas Company and 275,000 employees of the U.S. Steel Company. Leary’s vaccine was used frequently during the epidemic in state custodial institutions of the Northeast and by some private physicians. Duval and Harris reported immunizing approximately 5,000 people, most of whom were employees of large New Orleans companies. Almost without exception, those reporting on the use of these Pfeiffer’s bacillus vaccines reported that they were effective in preventing influenza.

The Faltering Case For Pfeiffer’s Bacillus

At first the apparent success of these vaccines served to increase confidence in the role played by Pfeiffer’s bacillus. But other evidence was accumulating. Initially, when observers reported difficulty isolating Pfeiffer’s bacillus from influenza cases, they found their technique and experience questioned. But slowly the evidence against Pfeiffer’s bacillus mounted, first ambiguously and then emphatically. J.J. Keegan, a naval medical officer working in the Boston area, published an early report on studies undertaken during an outbreak of 2,000 cases in the First Naval District during the two-week period between August 28 and September 11, 1918. Keegan made a special effort to study the outbreak bacteriologically. He had difficulty isolating Pfeiffer’s bacillus from throat washings or from sputum in both influenza cases and from patients admitted to the hospital with other conditions. He wondered whether the organism might be harbored in the sinuses or some other place more inaccessible to him. When he resorted to lung punctures in life and lung cultures at postmortem, he succeeded in isolating Pfeiffer’s bacillus in 82.6% of 23 cases.

Other ambiguous results came from Edwin Jordan, a future American influenza expert. Jordan reported on a large bacteriological study of patients diagnosed with influenza and with other diseases during and after the epidemic at the University of Chicago. He reported finding no consistent bacteriology in his cases. No microorganism was present in all influenza cases. Although he identified Pfeiffer’s bacillus in 64% of influenza cases, and this was more frequent than any other organism, its relative abundance varied a great deal among cases. He also isolated B. influenzae in 14% of colds and other infections.

A group from the medical staff of Cook County Hospital in Chicago undertook a careful study using 3,000 blood agar culture plates and procedures that they held should have detected B. influenzae, if it were present. They found that Pfeiffer’s bacillus was present in only a small number of cases: in only 4% of cultures made from washed sputum samples and in only 8.7% of postmortem lung cultures. They did find the organism in near pure culture in the lungs of a soldier who had died of influenzal pneumonia. They regarded Pfeiffer’s bacillus as the cause of that case of pneumonia. They found that pneumococci were the most common organisms isolated in this study, appearing in 70% of sputum cultures and in 38% of throat swab cultures. Type IV pneumococci were isolated in 50% of lung cultures made at autopsy. Types I–III were all also present but at lesser frequencies.

By early 1919, evidence was running more strongly against Pfeiffer’s bacillus. In February, David Davis, employing strict morphological and culture criteria, reported that he had succeeded in isolating what he identified as B. influenzae in only 8% of 62 cases of influenza he studied. As noted, he had earlier isolated this organism in higher percentages of cases of measles, varicella, tuberculosis, and pertussis. There was no doubt, he argued, that Pfeiffer’s bacillus was pathogenic for humans. He had isolated it from the spinal fluid in all cases of meningitis accompanying bronchopneumonia where B. influenzae was also present in pure or nearly pure culture. He concluded that whatever the cause of influenza might be, its most serious features were due to secondary invaders including streptococci, pneumococci, and B. influenzae. Frederick Lord and colleagues at Boston reached similar conclusions. Like Davis, Lord had already isolated B. influenzae from diseases other than influenza. In this pandemic, he and his colleagues isolated organisms resembling Pfeiffer’s bacillus in 84% of 38 hospitalized influenza cases, but also in 41% of the throats of members of the Harvard Students’ Army Training Corps, who had no record of illness for the previous three months. Lord concluded that B. influenzae should be regarded as a part of the normal flora of the human throat, but that there was no way to be certain whether the organisms found in normal throats and in other diseases with similar morphology and culture and staining characteristics were really identical to those found in influenza.

There remained, it seemed, a possibility that would clarify recent bacteriological findings and still rescue a place for Pfeiffer’s bacillus in the etiology of influenza. Perhaps, as would prove to be the case with diphtheria, there was a pseudo-influenza bacillus or different strains of B. influenzae, not all of which caused influenza. In that case, the finding of organisms morphologically identical to Pfeiffer’s bacillus in other diseases was not evidence against the role of Pfeiffer’s bacillus in influenza.

Several researchers investigated this possibility by trying to type strains of Pfeiffer’s bacillus, but their findings did little to buttress faith in B. influenzae’s role in influenza. F.H. Rapoport, a naval medical officer from Chelsea, Massachusetts, employed the complement fixation test for antibodies to B. influenzae in convalescent sera from cases of influenzal pneumonia and from normal control sera. He concluded that specific antibodies against Pfeiffer’s bacillus were formed during convalescence from pneumonia accompanying influenza, but that these had weak complement-binding properties. He could not determine whether one or more strains of Pfeiffer’s bacillus were circulating during the epidemic, although he observed that polyvalent antigens in his samples gave no better results than did monovalent ones.

Park and his associates studied cultures taken from 100 cases of influenza. In some cases, cultures were taken repeatedly over time. Careful antigen typing showed that there was a large variety of types of B. influenzae, that the organisms taken from an individual were quite stable over time, but that there were differences among the many types isolated from different individuals. He suggested that, like pneumococcus, B. influenzae had over the years in the throats of healthy carriers altered into distinct types. Pfeiffer’s bacillus in cases of influenza, he concluded, must be regarded as a secondary invader.

Alternative Etiologies, Other Vaccines

Other candidates had been proposed as the cause of influenza during the pandemic, but these were disposed of rather quickly. An Army medical officer, Captain George Mathers, who died of influenza during his investigation, isolated and characterized a streptococcus that produced a green color on blood agar plates. At Fort Mead, he isolated his green-producing streptococcus from 87% of influenza and pneumonia cases, while he was able to isolate Pfeiffer’s bacillus in only 58% of these cases.

The Mathers streptococcus attracted some attention during the early months of the pandemic. Jordan, for example, systematically looked for it in his study but found no evidence that made it seem a more probable cause than B. influenzae. Then, in both Europe and America, investigators considered the possibility that influenza might be caused by a filterable virus. At issue was the disputed finding that influenza could be caused in humans by inoculation of material from the noses or throats of influenza patients that had been passed through a bacterial filter. French and Japanese investigators had reported succeeding in transferring influenza by this method. American researchers failed to confirm these findings. The researchers from Cook County Hospital used this method to inoculate seven human volunteers without causing disease. They did the same with cultures made from the lungs of influenza pneumonia victims and inoculated two Rhesus monkeys with similar results. Other laboratory and human inoculation experiments aimed at detecting a filterable virus were also negative. These negative findings were also confirmed by extensive human experiments with influenza sponsored by the U.S. Navy and the U.S. Public Health Service.

As confidence in the role of Pfeiffer’s bacillus in influenza waned, the strategy of prevention by vaccine changed. Vaccines developed later in the pandemic — and almost all developed in the middle of the country and on the West Coast—were composed of other organisms either singly or in mixtures. Increasingly, vaccines were justified as preventing the pneumonias that accompanied influenza. Killed streptococci vaccines were developed by a physician in Denver and by the medical staff of the Puget Sound Naval Yard. The latter was used among sailors and also among civilians in Seattle.

Mixed vaccines were more common. These typically contained pneumococci and streptococci. Sometimes staphylococci, Pfeiffer’s bacillus, and even unidentified organisms recently isolated in the ward or morgue were included. The most widely used, and historically the most interesting, was the vaccine produced by Edward C. Rosenow of the Mayo Clinic’s Division of Experimental Bacteriology. Rosenow argued that the exact composition of a vaccine intended to prevent pneumonia had to match the distribution of the lung-infecting microbes then in circulation. For that reason, he insisted that the composition of his vaccine had to be frequently readjusted. His initial vaccine consisted of killed bacteria in these proportions: 30% pneumococci types I, II, and III; 30% pneumococci type IV and a “green-producing diplostreptococcus;” 20% hemolytic streptococci; 10% staphylococcus aureus; and 10% B. influenzae. He later dropped Pfeiffer’s bacillus entirely. The Mayo Clinic distributed Rosenow’s vaccine widely to physicians in the upper Midwest. No one seems to know for sure how many people received this vaccine, but, through physicians, Rosenow received returns for 93,000 people who had received all three injections, 23,000 who had received two injections, and 27,000 who had received one. Rosenow’s vaccine received even wider distribution. It was adopted by the City of Chicago. The Laboratories of the Chicago Health Department produced more than 500,000 doses of the vaccine. Some of it was distributed to Chicago physicians and the rest was turned over to the state health department for use throughout Illinois.

Vaccine Controversy And Standards For Vaccine Trials

As was the case with Pfeiffer’s bacillus vaccines, most of the early reports on the use of these mixed vaccines indicated they were effective. Readers of American medical journals in 1918 and for much of 1919 were thus faced with the strange circumstance that all vaccines, regardless of their composition, their mode of administration, or the circumstances in which they were tested, were held to prevent influenza or influenzal pneumonia. Something was clearly wrong. The medical profession had at the time no consensus on what constituted a valid vaccine trial, and it could not determine whether these vaccines did any good at all. The lack of agreed-upon standards was exacerbated by the informal editorial procedures and the absence of peer review in scientific publication in 1918. During the pandemic of 1918–1919, the profession was forced to develop standards for vaccine trials. Park and George McCoy, director of the Hygienic Laboratory of the Public Health Service, led the assault pointing out the fallacies in design or inference of current reports. Most trials began after the first cases of influenza had appeared locally, often after the epidemic peak had passed, and hence the most susceptible may already have been attacked and could not appear in the vaccinated group, and the more resistant were likely to be assigned to the vaccinated group. Little effort was usually made to minimize selection bias in assignments to experimental or control arms or to match each group by age, sex, and exposure. And too many trials operated with poor observation and imperfect data collection.

McCoy arranged his own trial of the Rosenow vaccine produced by the Laboratories of the Chicago Health Department. He and his associates worked in a mental asylum in California where they could keep all subjects under close observation. They immunized alternate patients younger than age 41 on every ward, completing the last immunization 11 days before the local outbreak began. Under these more controlled conditions, Rosenow’s vaccine offered no protection whatsoever. McCoy’s article appeared as a one-column report in the December 14, 1918, edition of the Journal of the American Medical Association (JAMA).

At the meeting of the American Public Health Association (APHA) later that month, McCoy and Park used their positions on the Executive Sub-committee on the Bacteriology of the 1918 Epidemic of Influenza to issue a manifesto that appeared in APHA’s “Working Program against Influenza.” APHA declared that because the cause of influenza was unknown, there was no logical basis for a vaccine to prevent the disease. There was a logical basis for believing that a vaccine to prevent the secondary infections might be developed, but there was no evidence that any of the vaccines currently available were effective. The association then specified the criteria that a trial must meet, if its conclusions were to be valid. There must be a control group, the association specified, and the vaccinated and the control group must be equal in size. The relative susceptibilities of the two groups must be equivalent as determined by age, sex, and prior exposure. Their degree of exposure must be of equal duration and intensity, and should take place during the same phase of the epidemic.

The reformers’ campaign had an impact. Following its publication — although the basic design faults of many trials remained — some authors now acknowledged shortcomings in their data or qualified their conclusions, and a few cited APHA’s new standards as authoritative. By the beginning of 1919, Rosenow, the most vocal defender of vaccines, found himself on the defensive. During the discussion of his paper at APHA’s annual meeting, he faced hostile comments from both McCoy and Victor Vaughan. The next month, JAMA ran an anonymous critical editorial accompanying his first article on the use of his vaccine. Perhaps the best evidence that professional standards were changing is found in two studies sponsored by the Metropolitan Life Insurance Company during the 1919–1920 influenza season. Both were unprecedented in the influenza literature in the care taken in trial design and analysis. Park and his associate, Anna Von Sholly, studied the use of two mixed vaccines among the employees of the home office of Met Life. Edwin Jordan and W.B. Sharp studied the effects of a single mixed vaccine in three residential schools and two large mental hospitals in Illinois. While adhering to the standards APHA had set forth, both studies concluded the vaccines used were ineffective.

Epidemiological Studies

American epidemiologists also devoted much attention to the 1918–1919 pandemic. Some of their studies — such as the substantial study on the epidemic in Connecticut by Winslow and Rogers, or the study of trends from 1910 to 1918 that W.H. Frost prepared for the Public Health Service, or Raymond Pearl’s statistical analysis of the epidemic curves of major American cities — were large-scale studies based on mass mortality data. Some of the more illuminating, however, were smaller-scale studies in which chains of transmission could be traced and incubation periods estimated in small, isolated populations such as inmates in a prison or residents on a small island. Among the most important were studies that acknowledged that accurate information on cases of influenza, rather than simply influenza and pneumonia deaths, was both lacking and critically important. The Public Health Service made a major effort to obtain records of illness through household surveys it conducted in 10 communities across the nation in which it was already doing research. A more intensive study was undertaken by Warren T. Vaughan in a population of 10,000 in six carefully chosen districts in Boston during the 1920 flu season. He also obtained information retrospectively on household illness during 1918–1919.

This epidemiological research confirmed many of the findings from 1889–1890 about pandemic influenza’s rapid spread, explosive local outbreaks, and very high morbidity rates. Frost’s analysis of the household returns show a range of local influenza morbidity rates ran from 150 to 530 cases per 1,000, although both he and Vaughan concluded that 200 per 1,000 was more typical for 1918–1919. Those enormously high rates of incidence explained how a disease with case fatality rates these authors found to range from 0.8% to 3.1% could cause so many deaths. These studies also showed that differences in case fatality rates were more important than differences in incidence rates in explaining the age group mortality patterns, including the high death rates among young adults during the pandemic.

Vaughan was unusual in paying attention to the question of population immunity. Although the cause of influenza must have been widely distributed in his districts in 1918–1919, some people showed remarkable resistance to the disease. Fifty-five percent of those in his study groups who shared a bed with an influenza victim during the pandemic escaped the disease. He argued that the patterns of incidence and death during the 1918–1919 pandemic could not be explained by immunity acquired during the pandemic of 1889–1890, and he suggested, perhaps more sagaciously than he realized, that understanding of herd immunity would be the key to understanding the epidemiology of influenza. If measles produced no lasting immunity, he pointed out, its outbreaks in cities would be as explosive as those of the great pandemic of 1918–1919.

Perhaps the most interesting epidemiological studies conducted during the 1918–1919 pandemic were the human experiments conducted by the Public Health Service and the U.S. Navy under the supervision of Milton Rosenau on Gallops Island, the quarantine station in Boston Harbor, and on Angel Island, its counterpart in San Francisco. The experiment began with 100 volunteers from the Navy who had no history of influenza. Rosenau was the first to report on the experiments conducted at Gallops Island in November and December 1918. His first volunteers received first one strain and then several strains of Pfeiffer’s bacillus by spray and swab into their noses and throats and then into their eyes. When that procedure failed to produce disease, others were inoculated with mixtures of other organisms isolated from the throats and noses of influenza patients. Next, some volunteers received injections of blood from influenza patients. Finally, 13 of the volunteers were taken into an influenza ward and exposed to 10 influenza patients each. Each volunteer was to shake hands with each patient, to talk with him at close range, and to permit him to cough directly into his face. None of the volunteers in these experiments developed influenza. Rosenau was clearly puzzled, and he cautioned against drawing conclusions from negative results. He ended his article in JAMA with a telling acknowledgement: “We entered the outbreak with a notion that we knew the cause of the disease, and were quite sure we knew how it was transmitted from person to person. Perhaps, if we have learned anything, it is that we are not quite sure what we know about the disease.”

The research conducted at Angel Island and that continued in early 1919 in Boston broadened this research by inoculating with the Mathers streptococcus and by including a search for filter-passing agents, but it produced similar negative results. It seemed that what was acknowledged to be one of the most contagious of communicable diseases could not be transferred under experimental conditions.

The Pandemic And Biomedical Knowledge

While the experience of the great pandemic of 1918–1919 had given American medical researchers a heightened appreciation of the dangers of pandemic influenza, and while it permitted epidemiologists to enlarge the fund of descriptive information on influenza outbreaks, it had done little to unlock the mysteries of the disease. If anything, the experience of 1918–1919 served to deconstruct existing biomedical knowledge.

This void in fundamental knowledge would not be filled soon. When Jordan published his massive, 500-page authoritative synthesis of the influenza literature in 1927, the most basic and fundamental features of influenza were still unexplained. Jordan told his readers that influenza could only be defined by its pattern of occurrence — its epidemiology. Its cause was unknown, and its pathology was indefinite. It was uncertain whether there was acquired immunity for influenza, and, if there was, how long it lasted. Why pandemics occurred when they did and why they spared some places were also unknown. It was also uncertain whether the disease called influenza that occurred every year in sporadic cases and small outbreaks was the same disease that circulated in the pandemics. He continued the practice of distinguishing “influenza” from “epidemic influenza.”

Jordan did suggest that changes in virulence of the still unknown agent of influenza might be important and that this agent might be filterable, but in 1927 these were still speculations for which there was no direct evidence. In short, the three decades that had passed since Leichtenstern published his major synthesis had seen remarkably little addition to the fund of basic scientific knowledge of influenza, in spite of concerted efforts by researchers employing the best available research tools.

source: NIH with References

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